Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia.
نویسندگان
چکیده
Infections constitute a principal cause of morbidity and mortality in sickle cell anemia (SCA). Here we present evidence to suggest that a polymorphism (G-463A MPO) in the gene encoding the myeloperoxidase (MPO) enzyme, important for the host defense system, may significantly increase susceptibility to infection in SCA.
منابع مشابه
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عنوان ژورنال:
- Haematologica
دوره 90 7 شماره
صفحات -
تاریخ انتشار 2005